the sesame lignan sesamin attenuates vascular permeability in rats with streptozotocin-induced diabetes: involvement of oxidative stress

نویسندگان

mehrdad roghani department of physiology, school of medicine and medicinal plant research center, shahed university, ir iran +98-2188964792, [email protected]; department of physiology, school of medicine and medicinal plant research center, shahed university, ir iran +98-2188964792, [email protected]

tourandokht baluchnejadmojarad department of physiology, school of medicine, tehran university of medical sciences, ir iran

farshad roghani dehkordi department of physiology, school of medicine, tehran university of medical sciences, ir iran

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The Sesame Lignan Sesamin Attenuates Vascular Permeability in Rats with Streptozotocin-Induced Diabetes: Involvement of Oxidative Stress

Background: Cardiovascular disorders are a major cause of morbidity and mortality in diabetic patients. Increased vascular permeability is a hallmark of diabetic vasculopathy, and the administration of natural products with antioxidant activity could restore vascular function. Objectives: In this study, the effect of chronic treatment with sesamin on vascular permeability in rats with streptozo...

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Diosgenin attenuates cardiac oxidative stress in streptozotocin- induced diabetic rat

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Sesame effects on testicular damage in streptozotocin-induced diabetes rats

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Background: It has been proposed that oxidative stress may contribute to the development of testicular abnormalities in diabetes. Morus alba leaf extract (MAE) has hypoglycemic and antioxidant properties. We, therefore, explored the impact of the administration of MAE on steroidogenesis in diabetic rats. Methods: To address this hypothesis, we measured the serum level of glucose, insulin, and f...

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Effects of Sesame Butter (Ardeh) versus Sesame Oil on Metabolic and Oxidative Stress Markers in Streptozotocin-Induced Diabetic Rats

Background: Diabetes is one of the most common metabolic disorders and is related to oxidative-stress-induced diseases. Given the role of dietary antioxidants in the control and prevention of diabetes, this study aimed to examine the effects of sesame butter versus sesame oil on the serum levels of glucose, lipid profile, and oxidative stress biomarkers in diabetic rats.Methods: Forty male albi...

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Sesame effects on testicular damage in streptozotocin-induced diabetes rats

OBJECTIVE(S) Reproductive dysfunction is a consequence of diabetes. Diabetes is associated with changes in testicular tissue. Sesame oil contains large amounts of polyunsaturated fatty acids and lignin with antioxidant activity, vitamin E, and monounsaturated fatty acid (MUFA). The present study investigated the effects of sesame on testis histology and male reproductive parameters in streptozo...

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عنوان ژورنال:
international journal of endocrinology and metabolism

جلد ۹، شماره ۱، صفحات ۲۴۸-۲۵۲

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